PDRN Salmon DNA

When your skin shows signs of biological decline.

Loss of firmness, extreme dryness, uneven texture, or sensitivity do not appear by chance. They are signs that your skin has lost its ability to repair itself. PDRN reactivates this natural function.

FDA-approved PDRN Salmon DNA

1050+ treatments performed

Licensed medical team

What is the PDRN and how does it work?

PDRN is a regenerative active ingredient derived from salmon DNA. It stimulates cell repair, improves hydration, and boosts collagen production.

PDRN does not beautify or fill. It corrects biological processes damaged by age, sun damage, or oxidative stress. It is a salmon DNA extract that reactivates cellular repair function.

Where other options fail,
PDRN corrects.

Skin problem	PDRN	Hyaluronic	Vitamin C
Lack of functional collagen	Yes	Yes	No
Persistent inflammation	Yes	No	No
Impaired cell regeneration	Yes	No	Yes
Reactive/sensitive skin	Yes	No	No

Founded in 2002, PROLLENIUM® one of the select few manufacturers to have received FDA approval for its state-of-the-art facilities. Emphasized in their dedication to meet the highest standards in the industry, in everything we do.

Boost your results after Microneedling.

PDRN is not a standalone treatment, it’s a powerful add-on that enhances your results.

Applied right after RF Microneedling or Microneedling, this step activates deep repair and cellular recovery at the perfect moment.

It only takes 10 minutes. No discomfort. No downtime.
Ask for it at your next visit and give your skin the regeneration it deserves.

What issues does PDRN help correct?

PDRN not only treats superficial symptoms, but also activates deep biological processes to regenerate the skin from within. Here’s how it transforms your skin at the cellular level.

Limited cell repair

When the skin loses its ability to repair itself after sun damage, acne, or aging.

Structural dehydration

Strengthens the skin barrier and increases water retention. Leaves skin soft, supple, and radiant.

Impaired firmness and elasticity

Loss of support in the cheeks, jaw, or neck.

Hypersensitive or reactive skin

Redness, burning, or itching in response to minimal stimuli.

Silent inflammation

Microinflammations that affect tone and texture without apparent cause.

What to expect after you add PDRN to your treatment?

PDRN is not just a topical solution. It’s a regenerative therapy that works with your skin’s biology to trigger deep repair. Here’s how it works:

1

We assess your skin condition.

Before starting, a specialist evaluates your skin, goals, and medical background to tailor the protocol to your needs.

2

We apply the PDRN serum.

After Microneedling or RF Microneedling, we deliver the active compound directly into the dermis to stimulate regeneration and hydration.

3

Subtle, natural, and lasting improvement.

Your skin begins to heal from within. You’ll see visible changes in tone, texture, and firmness after each session, with no synthetic fillers involved.

PDRN is ideal after these treatments.

Plans and prices to add to your treatment.

1 PDRN tx

One-time boost / first-timers

$295

3 PDRN txs

For short treatment plans (3 sessions)

$695

4 PDRN txs

Matches 4-session protocols

$995

6 PDRN txs

Full 6-session course

$1415

Flexible payment options available starting at $11.80/month.

Just takes 10 minutes after your session.

Your safety, our standard.

At Perfect B, your results and safety come first always.

“We never compromise on safety from the product to the hands that apply it.”

500+ Verified 5 – star reviews

This is what feeling better looks like

Reliable Results

"I just noticed a significant improvement"

KAI XUAN

Comfort

"Trust me, there is a plan for you"

MARIANA MARTINEZ

Confidence

"I dont feel the need to wear make up every single day"

RACHEL MOSQUERA

Frequently asked questions.

How does microneedling with PDRN serum improve skin rejuvenation results?

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What role does salmon DNA play in regenerative medical skincare treatments?

Is PDRN part of modern regenerative medical therapies for skin?

How does microneedling PDRN affect the stratum corneum during skin repair?

What should I expect in microneedling before and after when using PDRN?

How does PDRN skincare improve skin texture and elasticity?

Is salmon DNA safe and effective in microneedling therapy?

Salmon DNA Microneedling: The PDRN Treatment Transforming Skin Repair

📍 What is PDRN and Why Is Salmon DNA Different?

Let’s start with the question most new patients ask: what is PDRN?

PDRN stands for polydeoxyribonucleotide. It is a biologically active compound extracted from purified salmon DNA. Thanks to its molecular similarity to human DNA, it is well-tolerated and works with your skin to stimulate natural repair, collagen production, and anti-inflammatory responses.

At Perfect B, we deliver pdrn treatment primarily through SkinPen microneedling serum, a targeted application method that ensures precise delivery into the skin’s receptive layers.

➔ Curious how PDRN therapy compares to other regenerative tools in clinical skincare? Explore whether it truly qualifies as a breakthrough in regenerative medicine in our in-depth review.

By focusing on salmon DNA delivery through microneedling instead of generic serums or injectables, we achieve a visible difference in tone, texture, and healing speed. This is especially true when paired with customized regen med protocols.

💧 The Power of Microneedling Serum with Salmon DNA

If you’re looking to improve skin texture, hydration, or elasticity, pairing microneedling serum with salmon DNA can yield exceptional results.

At Perfect B, we apply our PDRN serum directly after SkinPen microneedling, which creates controlled microchannels in the skin. This process allows the microneedling serum to reach deeper layers, where salmon DNA stimulates collagen, boosts hydration, and accelerates tissue renewal.

This method avoids unnecessary inflammation or downtime. Patients often experience:

Strengthened skin barrier function
Faster recovery after treatment
Improved elasticity
Noticeably smoother tone and fewer fine lines

This is not just a serum. It is a pdrn treatment powered by medical-grade regenerative care.

🧬 Salmon DNA vs. Over-the-Counter PDRN Skincare

There is a growing market of PDRN skincare products claiming to offer similar results. However, while over-the-counter PDRN skincare can support your regimen, it cannot replace in-office pdrn treatment combined with microneedling serum.

Here’s why:

Feature	At-Home PDRN Skincare	In-Clinic Microneedling Serum
PDRN source	Cosmetic-grade	Medical-grade salmon DNA
Penetration	Surface-level only	Dermal-level with SkinPen
Effect	Temporary hydration	Long-term repair and collagen support
Role in regen med plans	Maintenance only	Core regenerative component

We sometimes recommend PDRN skincare post-treatment, but the best results come from clinical application. This ensures that salmon DNA is delivered precisely where your skin needs it most.

➔ For a deeper dive into how PDRN aesthetic applications are reshaping skin health through advanced regenerative protocols.

🔄 How Salmon DNA Enhances Regen Med Protocols

In the world of regen med, salmon DNA has gained attention for its ability to support the skin’s natural healing and collagen formation processes.

When applied through microneedling serum, this DNA-based molecule can:

Activate A2A adenosine receptors, reducing inflammation
Promote new blood vessel growth
Stimulate fibroblast activity to support collagen remodeling
Provide nucleotides that feed into the skin’s DNA repair cycle

Together, these actions make pdrn treatment one of the most effective additions to any regen med plan designed to improve firmness, texture, and resilience.

🧪 What to Expect From PDRN Microneedling

Our microneedling serum protocol using salmon DNA includes three essential phases:

Consultation and Skin Analysis
We assess your skin health, treatment goals, and medical history to determine how PDRN treatment can fit into your personalized regen med plan.
SkinPen Microneedling with PDRN Serum
Immediately after microneedling, we apply the salmon DNA serum. This timing allows for maximum absorption and effectiveness.
Gradual Results
Over the days and weeks that follow, your skin restores tone, hydration, and elasticity. Most patients see cumulative improvements after three or four sessions.

💬 Final Thoughts: Why Salmon DNA Is a Game-Changer

At Perfect B, we do not treat salmon DNA as a trend. It is a critical part of our clinical toolkit for skin rejuvenation.

Our pdrn treatment strategy focuses on expert delivery, using only purified salmon DNA through SkinPen microneedling serum. This method allows us to target real skin challenges with scientific precision and personalized care.

Whether you are new to PDRN skincare or ready to improve your skin’s recovery after advanced treatments, we are here to guide you through a custom protocol that fits your needs.